Supercomputers: The Solution to Physical Test Limitations in Automotive Manufacturing

During the past few decades the world of science has changed, moving from physical experimentation alone to an environment in which simulations are of primary importance. In the automotive industry, research and design is now so advanced that it’s following in the footsteps of science and moving away from physical testing. Supercomputing has allowed automobile manufacturers to transition to a simulation-driven world. The innovative use of new materials in vehicle design is becoming the norm for automotive manufacturers — honeycomb structures and increased aluminum use being an example. With more advanced design elements coming into play, numerous manufacturing challenges are emerging; including the need for a greater number of … [Read more...]

Using HPC Techniques to Accelerate NGS Workflows

Life Sciences_small

Next-generation sequencing (NGS) describes the modern nucleotide sequencing technologies that allow analysis of genetic material with unprecedented speed and efficiency. Its advent is shifting genome assembly from a problem of laboratory-based chemistry to one well suited to high performance computing (HPC). In simple terms, NGS involves breaking up long DNA or RNA molecules into millions of small, fragments (50 to 200 nucleotides), defined as a “reads” to be assembled into larger fragments called contigs. The process of taking genetic material, processing it on a sequencer, passing it to an HPC system for assembly, and outputting digital information in a form useful for research is contained in a “workflow,” the end-to-end flow of … [Read more...]

The Definition of Insanity


Almost ten years ago, when I was working at Pfizer, I wrote a position paper for a W3C Workshop on Semantic Web in Life Sciences. In that paper, I pointed out several vexing problems then faced by pharmaceutical researchers that I thought could be alleviated by use of a powerful knowledge architecture such as that enabled by Semantic Web technologies. Among these problems were those you might classify as knowledge management problems, and they had much to do with effectively sharing information throughout a large research organization where specialized vocabularies and varied purposes can easily get in the way. Other problems I described were just good, old-fashioned informatics problems, in particular the creation of so-called "data … [Read more...]

Record LS-DYNA “car2car” Performance Paves the Way for Future Crash/Safety Simulation

Altair Webcast

A Cray supercomputer has set a speed record in a crash/safety simulation used by the automotive and aerospace industries. Leveraging the scalability of the Aries interconnect in the Cray® XC30™ supercomputer, engineers ran the “car2car” model, a 2.4-million element crash/safety simulation, in under 1,000 seconds. The LS-DYNA results are posted on, the site that was created to track the performance of HPC systems on actual engineering applications codes. In addition to the job turnaround record (931 seconds), the result set a record for the level of parallelism (3,000 cores). As the automotive and aerospace industries continue to run larger and more complex simulations, the performance and scalability of the applications … [Read more...]

Video Blog: Solutions that Enable Life Sciences Advances

Ted Slater

Advanced IT solutions are transforming the life sciences industry, and there are few better places to learn about how this is happening than the Bio-IT World Conference & Expo in Boston. The conference is coming up soon, and at Cray, we're excited to highlight our computing, storage and analysis solutions. Ted Slater, senior solutions architect for life sciences at YarcData, a Cray company, will present on Wednesday, April 30, and talk about how YarcData’s Urika technology is fueling major advances. Ted's presentation, "Learn How YarcData's Graph Analytics Appliance Makes It Easy to Use Big Data in Life Sciences," is about how data-intensive research is rising in life sciences and how YarcData systems provide the functionality … [Read more...]